[18F]Sodium Fluoride

[18F]Sodium Fluoride for injection (Natrii Fluoridi (18F)solutio iniectabilis): sterile and bacterial endotoxine-free solution , for diagnostic use, containing 18F- fluoride isotope, minimum 98,5% of the total radioactivity, in the form of sodium fluoride (Ph.Eur.). Activity: 400 MBq-90 GBq.

The Sodium (18F) Fluoride was first introduced as a skeletal PET imaging agent by Blau M in 1962. It is used for the detection of bone lesions in various malignancies (metastasis) and was suggested as an alternative to 99mTc-methylene diphosphonate (99mTc-DMP) bone scintigraphy.