PhD scholarship: In situ Industrial Dosimetry for Polymer based Medical Devices

Thursday 07 Jul 22

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The ionizing radiation dosimetry group in the Hevesy Division, DTU Health Technology, is seeking a candidate for a PhD position to develop a new industrial dosimetry system for ensuring patient safety in medical device sterilization. The work will be carried out in close national collaboration with Coloplast and DTU Chemistry and internationally with the National Physical Laboratory, UK, and the National Research Council, Canada.

The Hevesy Division carries out research, innovation, and research-based consultancy in the fields of dosimetry, radiation processing, radiation therapy and diagnostics, and radioisotope production. The division presently consists of approx. 40 people including researchers, technicians, and PhD students.  

Background
About half of all single-use medical devices are sterilized using ionizing radiation, and this amount is increasing. During sterilization it is crucial that the device receives enough radiation dose to obtain the required level of sterility, but equally important that the dose does not exceed the device’s tolerance level for maintaining its functionality and thereby ultimately compromising the patient’s health and well-being. The overall objective of this PhD project is therefore to develop a new method for measuring dose directly from the bulk material of the medical device. The end goal is to provide a method for dose prediction already in the medical device design phase leading to (i) cost savings in production and design optimization and (ii) enabling the validation of the radiation sterilization process to be integrated into the product development. The project is funded by the Independent Research Fund Denmark.

Job description
The objective of this PhD project is to develop a method for measurement of dose inside a complex medical device, for example, based on alanine powder mixed into the polymer material of the device. This approach requires a fundamental understanding of the dosimetric behaviour of alanine when imbedded into a range of matrix polymer materials. The mixes will be characterized, tested, and cast into simplified medical devices for irradiation and dose measurement of the bulk matrix material.

These measurements will be used as an input to validate a Monte Carlo tool that will be developed during the project by the PhD student. This tool will be used for predicting both surface and bulk dose in complex devices. The project is interdisciplinary in its nature and will therefore be carried out in close national collaboration with the R&D section at Coloplast and DTU Chemistry.

Qualifications
The candidate should have a two-year master's degree (120 ECTS points) or an equivalent degree in engineering and preferably with a prior knowledge of polymer chemistry and an interest in radiation physics and applications of ionizing radiation.

Approval and enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU's rules for the PhD education.  

We offer
We offer an exciting and challenging job in an international academic environment with excellent possibilities for professional and personal development. The successful candidate will work in an environment with activities and expertise in radiation physics, dosimetry, radiation processing, medical applications of radionuclides and radioisotope production.

Salary and terms of employment
The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union.
The period of employment is 3 years. The candidate should be able to start before the end of 2022.


The place of work is DTU Health Tech at Risø campus in Roskilde.

Further information
Further information may be obtained from Senior Scientist Christina Ankjærgaard, cank@dtu.dk, +45 6165 6929 or Head of section Claus E. Andersen, clan@dtu.dk, +45 4677 4912.


You can read more about DTU Health Tech at www.healthtech.dtu.dk/english.

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU.

Application procedure
Your complete online application must be submitted no later than 29 August 2022 (Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale

You may apply prior to ob­tai­ning your master's degree but cannot begin before having received it.

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Techs expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies. The department has a scientific staff of about 210 persons, 140 PhD students and a technical/administrative support staff of about 160 persons, of which a large majority contributes to our research infrastructure and related commercial activities.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 13,400 students and 5,800 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.