Nayere Taebnia

PhD project by Nayere Taebnia

Name: Nayere Taebnia
Project Title:
A human-gut-on-a-chip for drug delivery testing and disease modelling: breaking through the gut barrier
Group:
Colloids and Biological Interfaces (CBIO)
Supervisor(s):
Thomas L. Andresen (main supervisor) and Niels Bent Larsen (co-supervisor)

Project Description:
This project is aimed at developing a biomimetic human gut-on-a-chip platform, fabricated using stereolithographic high-resolution 3D printing. The chip recapitulates the complex crypt-villus geometry of the native tissue as well as the underlying capillaries, and supports epithelial cells growth and differentiation. This platform will be further coupled with state of the art microscopes to visualize peptide drugs transport across the gut barrier.

Perspective:
Our gut-on-a-chip platform provides a powerful alternative in vitro model to advance our understanding of intestinal physiology and its role in drug uptake and personalized medicine.

Kontakt

Nayere Taebnia
Postdoc
DTU Sundhedsteknologi
91 74 95 52

Kontakt

Thomas Lars Andresen
Institutdirektør, professor
DTU Sundhedsteknologi
25 37 44 86

Kontakt

Niels Bent Larsen
Sektionsleder, Professor
DTU Sundhedsteknologi
45 25 81 61