Consultant in Drug Delivery

Thursday 08 Apr 21

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DTU Health Tech is looking for an experienced formulation specialist to join our BII project team working with Locally Sustained Gene Therapy. Experience with nanoparticle formulation and in vitro cell testing is required.

The job
Our aim is to develop a technology for localized gene therapy where the first technological objective is to generate a transfection system for immune activating cytokines that can stimulate immunologic elimination of solid cancers.


The successful candidate will support the creation of formulation strategies for delivery of RNA- and DNA-based transfection systems. The candidate will contribute to analysis and quality control of the transfection systems using dynamic light scattering, HPLC, and fluorescence spectroscopy. Additionally, in vitro transfection of cells and flowcytometric analysis will be vital to support the team’s progress.

Responsibilities:

  • Assist the formulation of RNA and DNA transfection vectors
  • Participate in development of depot formulations for release of transfection vectors
  • Contribute to stability studies
  • Assist the bench testing of formulations
  • Provide input in evaluation of in vitro transfection efficiency in cell cultures.
  • Contribute to documentation and communication of obtained results. 

Our expectations of you
You must hold a PhD degree (or equivalent) ideally in chemistry, pharmaceutical or biological science with a focus on formulation and biological evaluation of drug delivery systems.

Qualifications:

  • Knowledge of lipid and polymeric nanoparticles
  • Experience with HPLC analysis and dynamic light scattering
  • Experience with fluorescence spectroscopy
  • Experience with cell cytotoxicity assays and flow cytometry analysis
  • Knowledge of relevant biological targets for cancer therapy is an advantage

What we offer in return
We offer an interesting and challenging job in an international atmosphere with the focus on research, teaching, innovation and scientific advice for the benefit of the surrounding community. We place emphasis on a high level of professionalism among our staff, so skills development is an integral part of our organization. We offer a great flexibility in the position. In the area of technical and natural sciences, DTU is one of the leading research and education institutions in Europe.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

The position is a permanent position starting 1 June 2021 (or according to mutual agreement).

Application and contact
Please submit your online application no later than Thursday, 22 April 2021 (Danish time). Open the “Apply online” link, fill out the form and attach your motivated application, CV and exam certificates. 


If you would like additional information about the position, please contact Assoc. Prof. Jonas R. Henriksen, +45 4058 2866 or Project coordinator Ashley Montgomery, +45 3164 2424.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Techs expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies. The department has a scientific staff of about 175 persons, 130 PhD students and a technical/administrative support staff of about 80 persons.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,000 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. Our main campus is in Kgs. Lyngby north of Copenhagen and we have campuses in Roskilde and Ballerup and in Sisimiut in Greenland.