Publications

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2022
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Cancer-related Mutations with Local or Long-range Effects on an Allosteric Loop of p53

Degn, Kristine ; Beltrame, Ludovica ; Dahl Hede, Freja ; Sora, Valentina ; Nicolaci, Vincenzo ; Vabistsevits, Marina ; Schmiegelow, Kjeld ; Wadt, Karin ; Tiberti, Matteo ; Lambrughi, Matteo ; Papaleo, Elena
in: Journal of Molecular Biology, vol: 434, issue: 17

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1016/j.jmb.2022.167663

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Directed Evolution of (R)-2-Hydroxyglutarate Dehydrogenase Improves 2-Oxoadipate Reduction by 2 Orders of Magnitude

Saez-Jimenez, Veronica ; Scrima, Simone ; Lambrughi, Matteo ; Papaleo, Elena ; Mapelli, Valeria ; Engqvist, Martin K.M. ; Olsson, Lisbeth
in: ACS Synthetic Biology, vol: 11, issue: 8, pages: 2779-2790

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1021/acssynbio.2c00162

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DisProt in 2022

Quaglia, Federica ; Mészáros, Bálint ; Salladini, Edoardo ; Hatos, András ; Pancsa, Rita ; Chemes, Lucía B ; Pajkos, Mátyás ; Lazar, Tamas ; Peña-Díaz, Samuel ; Santos, Jaime ; Ács, Veronika ; Farahi, Nazanin ; Fichó, Erzsébet ; Aspromonte, Maria Cristina ; Bassot, Claudio ; Chasapi, Anastasia ; Davey, Norman E. ; Davidović, Radoslav ; Dobson, Laszlo ; Elofsson, Arne ; Erdős, Gábor ; Gaudet, Pascale ; Giglio, Michelle ; Glavina, Juliana ; Iserte, Javier ; Iglesias, Valentín ; Kálmán, Zsófia ; Lambrughi, Matteo ; Leonardi, Emanuela ; Longhi, Sonia ; Macedo-Ribeiro, Sandra ; Maiani, Emiliano ; Marchetti, Julia ; Marino-Buslje, Cristina ; Mészáros, Attila ; Monzon, Alexander Miguel ; Minervini, Giovanni ; Nadendla, Suvarna ; Nilsson, Juliet F. ; Novotný, Marian ; Ouzounis, Christos A. ; Palopoli, Nicolás ; Papaleo, Elena ; Pereira, Pedro José Barbosa ; Pozzati, Gabriele ; Promponas, Vasilis J. ; Pujols, Jordi ; Rocha, Alma Carolina Sanchez ; Salas, Martin ; Sawicki, Luciana Rodriguez ; Schad, Eva ; Shenoy, Aditi ; Szaniszló, Tamás ; Tsirigos, Konstantinos D. ; Veljkovic, Nevena ; Parisi, Gustavo ; Ventura, Salvador ; Dosztányi, Zsuzsanna ; Tompa, Peter ; Tosatto, Silvio C.E. ; Piovesan, Damiano
in: Nucleic Acids Research, vol: 50, issue: D1, pages: D480–D487

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1093/nar/gkab1082

 

MutateX: an automated pipeline for in silico saturation mutagenesis of protein structures and structural ensembles

Tiberti, Matteo ; Terkelsen, Thilde ; Degn, Kristine ; Beltrame, Ludovica ; Cremers, Tycho Canter ; da Piedade, Isabelle ; Di Marco, Miriam ; Maiani, Emiliano ; Papaleo, Elena
in: Briefings in Bioinformatics

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2022     |    DOI: https://doi.org/10.1093/bib/bbac074

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Redefining germline predisposition in children with molecularly characterized ependymoma

Foss-Skiftesvik, Jon ; Stoltze, Ulrik Kristoffer ; van Overeem Hansen, Thomas ; Ahlborn, Lise Barlebo ; Sørensen, Erik ; Ostrowski, Sisse Rye ; Kullegaard, Solvej Margrete Aldringer ; Laspiur, Adrian Otamendi ; Melchior, Linea Cecilie ; Scheie, David ; Kristensen, Bjarne Winther ; Skjøth-Rasmussen, Jane ; Schmiegelow, Kjeld ; Wadt, Karin ; Mathiasen, René
in: Acta neuropathologica communications, vol: 10

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1186/s40478-022-01429-1

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Structural Details of BH3 Motifs and BH3-Mediated Interactions

Sora, Valentina ; Papaleo, Elena
in: Frontiers in Molecular Biosciences, vol: 9

Type: Review (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.3389/fmolb.2022.864874

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The Cancermuts software package for the prioritization of missense cancer variants

Tiberti, Matteo ; Di Leo, Luca ; Vistesen, Mette Vixø ; Kuhre, Rikke Sofie ; Cecconi, Francesco ; De Zio, Daniela ; Papaleo, Elena
in: Cell Death & Disease, vol: 13

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1038/s41419-022-05318-2

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Unraveling membrane properties at the organelle-level with LipidDyn

Scrima, Simone ; Tiberti, Matteo ; Campo, Alessia ; Corcelle-Termeau, Elisabeth ; Judith, Delphine ; Foged, Mads Møller ; Clemmensen, Knut Kristoffer Bundgaard ; Tooze, Sharon A. ; Jäättelä, Marja ; Maeda, Kenji ; Lambrughi, Matteo ; Papaleo, Elena
in: Computational and Structural Biotechnology Journal, vol: 20, pages: 3604-3614

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1016/j.csbj.2022.06.054

2021
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A dual-reporter system for investigating and optimizing protein translation and folding in E. coli

Zutz, Ariane ; Hamborg, Louise ; Pedersen, Lasse Ebdrup ; Kassem, Maher M. ; Papaleo, Elena ; Koza, Anna ; Herrgård, Markus J. ; Jensen, Sheila Ingemann ; Teilum, Kaare ; Lindorff-Larsen, Kresten ; Nielsen, Alex Toftgaard
in: Nature Communications, vol: 12

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1038/s41467-021-26337-1

 

Bcl-xL Dynamics under the Lens of Protein Structure Networks

Sora, Valentina ; Sanchez, Dionisio ; Papaleo, Elena
in: Journal of Physical Chemistry B, vol: 125, issue: 17, pages: 4308-4320

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1021/acs.jpcb.0c11562