Publications

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2022
 

Acute central nervous system toxicity during treatment of pediatric acute lymphoblastic leukemia: phenotypes, risk factors and genotypes

Anastasopoulou, Stavroula ; Nielsen, Rikke Linnemann ; Als-Nielsen, Bodil ; Banerjee, Joanna ; Eriksson, Mats A. ; Helenius, Marianne ; Heyman, Mats M. ; Johannsdottir, Inga Maria ; Jonsson, Olafur Gisli ; MacGregor, Stuart ; Mateos, Marion K. ; Mayoh, Chelsea ; Mikkel, Sirje ; Myrberg, Ida Hed ; Niinimäki, Riitta ; Schmiegelow, Kjeld ; Taskinen, Mervi ; Vaitkeviciene, Goda ; Warnqvist, Anna ; Wolthers, Benjamin ; Harila-Saari, Arja ; Ranta, Susanna
in: Haematologica

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2022     |    DOI: https://doi.org/10.3324/haematol.2021.280016

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Can Machine Learning Models Predict Asparaginase-associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia

Nielsen, Rikke L. ; Wolthers, Benjamin O. ; Helenius, Marianne ; Albertsen, Birgitte K. ; Clemmensen, Line ; Nielsen, Kasper ; Kanerva, Jukka ; Niinimäki, Riitta ; Frandsen, Thomas L. ; Attarbaschi, Andishe ; Barzilai, Shlomit ; Colombini, Antonella ; Escherich, Gabriele ; Aytan-Aktug, Derya ; Liu, Hsi-Che ; Möricke, Anja ; Samarasinghe, Sujith ; van der Sluis, Inge M. ; Stanulla, Martin ; Tulstrup, Morten ; Yadav, Rachita ; Zapotocka, Ester ; Schmiegelow, Kjeld ; Gupta, Ramneek
in: Journal of Pediatric Hematology/Oncology, vol: 44, issue: 3, pages: e628-e636

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1097/MPH.0000000000002292

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Characteristics of white blood cell count in acute lymphoblastic leukemia

Helenius, Marianne ; Vaitkeviciene, Goda ; Abrahamsson, Jonas ; Jonsson, Ólafur Gisli ; Lund, Bendik ; Harila-Saari, Arja ; Vettenranta, Kim ; Mikkel, Sirje ; Stanulla, Martin ; Lopez-Lopez, Elixabet ; Waanders, Esmé ; Madsen, Hans O. ; Marquart, Hanne Vibeke ; Modvig, Signe ; Gupta, Ramneek ; Schmiegelow, Kjeld ; Nielsen, Rikke Linnemann
in: Pediatric Blood and Cancer, vol: 69

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1002/pbc.29582

 

Endothelial dysfunction and thromboembolism in children, adolescents, and young adults with acute lymphoblastic leukemia

Andrés-Jensen, Liv ; Grell, Kathrine ; Rank, Cecilie Utke ; Albertsen, Birgitte Klug ; Tuckuviene, Ruta ; Linnemann Nielsen, Rikke ; Lynggaard, Line Stensig ; Jarvis, Kirsten Brunsvig ; Quist-Paulsen, Petter ; Trakymiene, Sonata Saulyte ; Semaškevičienė, Rūta ; Saks, Kadri ; Jonsson, Olafur Gisli ; Frandsen, Thomas Leth ; Johansson, Pär Ingemar ; Schmiegelow, Kjeld
in: Leukemia, vol: 36, pages: 361-369

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1038/s41375-021-01383-2

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Large-Scale Functional Genomics Screen to Identify Modulators of Human β-Cell Insulin Secretion

Szczerbinska, Iwona ; Tessitore, Annamaria ; Hansson, Lena Kristina ; Agrawal, Asmita ; Lopez, Alejandro Ragel ; Helenius, Marianne ; Malinowski, Andrzej R. ; Gilboa, Barak ; Ruby, Maxwell A. ; Gupta, Ramneek ; Ämmälä, Carina
in: Biomedicines, vol: 10, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.3390/biomedicines10010103

2021
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Systematic Review of Pharmacogenetic Factors That Influence High-Dose Methotrexate Pharmacokinetics in Pediatric Malignancies

Taylor, Zachary L. ; Vang, Jesper ; Lopez-Lopez, Elixabet ; Oosterom, Natanja ; Mikkelsen, Torben ; Ramsey, Laura B.
in: Cancers, vol: 13, issue: 11

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.3390/cancers13112837

2020
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Big Data approaches for prediction of clinically relevant outcomes

Nielsen, Rikke Linnemann

Type: Ph.D. thesis

Status: Published     |    Year: 2020

 

Cardiovascular Risk Factors and Disease After Male Germ Cell Cancer

Lauritsen, Jakob ; Hansen, Merete Kjær ; Bandak, Mikkel ; Kreiberg, Michael Bay ; Skøtt, Julie Wang ; Wagner, Thomas ; Gundgaard Kier, Maria Gry ; Holm, Niels Vilstrup ; Agerbæk, Mads ; Gupta, Ramneek ; Dehlendorff, Christian ; Andersen, Klaus Kae ; Daugaard, Gedske
in: Journal of Clinical Oncology, vol: 38, issue: 6, pages: 584-592

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1200/jco.19.01180

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Data integration for prediction of weight loss in randomized controlled dietary trials

Nielsen, Rikke Linnemann ; Helenius, Marianne ; Garcia, Sara L. ; Roager, Henrik M. ; Aytan-Aktug, Derya ; Hansen, Lea Benedicte Skov ; Lind, Mads Vendelbo ; Vogt, Josef Korbinian ; Dalgaard, Marlene Danner ; Bahl, Martin I. ; Jensen, Cecilia Bang ; Muktupavela, Rasa ; Warinner, Christina ; Aaskov, Vincent ; Gøbel, Rikke ; Kristensen, Mette ; Frøkiær, Hanne ; Sparholt, Morten H. ; Christensen, Anders F. ; Vestergaard, Henrik ; Hansen, Torben ; Kristiansen, Karsten ; Brix, Susanne ; Petersen, Thomas Nordahl ; Lauritzen, Lotte ; Licht, Tine Rask ; Pedersen, Oluf ; Gupta, Ramneek
in: Scientific Reports, vol: 10, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1038/s41598-020-76097-z

 

Effects of germline DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia

Tulstrup, Morten ; Moriyama, Takaya ; Jiang, Chuang ; Grosjean, Marie ; Nersting, Jacob ; Abrahamsson, Jonas ; Grell, Kathrine ; Hjalgrim, Lisa Lyngsie ; Jónsson, Ólafur Gísli ; Kanerva, Jukka ; Lund, Bendik ; Nielsen, Stine Nygaard ; Nielsen, Rikke Linnemann ; Overgaard, Ulrik ; Quist-Paulsen, Petter ; Pruunsild, Kaie ; Vaitkeviciene, Goda ; Wolthers, Benjamin Ole ; Zhang, Hui ; Gupta, Ramneek ; Yang, Jun J. ; Schmiegelow, Kjeld
in: Blood, vol: 136, issue: 10, pages: 1161-1168

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1182/blood.2020005064