Publications

Publikationer rss feed

2021
  PDF

Systematic Review of Pharmacogenetic Factors That Influence High-Dose Methotrexate Pharmacokinetics in Pediatric Malignancies

Taylor, Zachary L. ; Vang, Jesper ; Lopez-Lopez, Elixabet ; Oosterom, Natanja ; Mikkelsen, Torben ; Ramsey, Laura B.
in: Cancers, vol: 13, issue: 11

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.3390/cancers13112837

2020
  PDF

Big Data approaches for prediction of clinically relevant outcomes

Nielsen, Rikke Linnemann

Type: Ph.D. thesis

Status: Published     |    Year: 2020

 

Cardiovascular Risk Factors and Disease After Male Germ Cell Cancer

Lauritsen, Jakob ; Hansen, Merete Kjær ; Bandak, Mikkel ; Kreiberg, Michael Bay ; Skøtt, Julie Wang ; Wagner, Thomas ; Gundgaard Kier, Maria Gry ; Holm, Niels Vilstrup ; Agerbæk, Mads ; Gupta, Ramneek ; Dehlendorff, Christian ; Andersen, Klaus Kae ; Daugaard, Gedske
in: Journal of Clinical Oncology, vol: 38, issue: 6, pages: 584-592

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1200/jco.19.01180

  PDF

Data integration for prediction of weight loss in randomized controlled dietary trials

Nielsen, Rikke Linnemann ; Helenius, Marianne ; Garcia, Sara L. ; Roager, Henrik M. ; Aytan-Aktug, Derya ; Hansen, Lea Benedicte Skov ; Lind, Mads Vendelbo ; Vogt, Josef Korbinian ; Dalgaard, Marlene Danner ; Bahl, Martin I. ; Jensen, Cecilia Bang ; Muktupavela, Rasa ; Warinner, Christina ; Aaskov, Vincent ; Gøbel, Rikke ; Kristensen, Mette ; Frøkiær, Hanne ; Sparholt, Morten H. ; Christensen, Anders F. ; Vestergaard, Henrik ; Hansen, Torben ; Kristiansen, Karsten ; Brix, Susanne ; Petersen, Thomas Nordahl ; Lauritzen, Lotte ; Licht, Tine Rask ; Pedersen, Oluf ; Gupta, Ramneek
in: Scientific Reports, vol: 10, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1038/s41598-020-76097-z

 

Effects of germline DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia

Tulstrup, Morten ; Moriyama, Takaya ; Jiang, Chuang ; Grosjean, Marie ; Nersting, Jacob ; Abrahamsson, Jonas ; Grell, Kathrine ; Hjalgrim, Lisa Lyngsie ; Jónsson, Ólafur Gísli ; Kanerva, Jukka ; Lund, Bendik ; Nielsen, Stine Nygaard ; Nielsen, Rikke Linnemann ; Overgaard, Ulrik ; Quist-Paulsen, Petter ; Pruunsild, Kaie ; Vaitkeviciene, Goda ; Wolthers, Benjamin Ole ; Zhang, Hui ; Gupta, Ramneek ; Yang, Jun J. ; Schmiegelow, Kjeld
in: Blood, vol: 136, issue: 10, pages: 1161-1168

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1182/blood.2020005064

  PDF

Genome-wide association meta-analysis of single-nucleotide polymorphisms and symptomatic venous thromboembolism during therapy for acute lymphoblastic leukemia and lymphoma in caucasian children

Mateos, Marion K. ; Tulstrup, Morten ; Quinn, Michael C.J. ; Tuckuviene, Ruta ; Marshall, Glenn M. ; Gupta, Ramneek ; Mayoh, Chelsea ; Wolthers, Benjamin O. ; Barbaro, Pasquale M. ; Ruud, Ellen ; Sutton, Rosemary ; Huttunen, Pasi ; Revesz, Tamas ; Trakymiene, Sonata S. ; Barbaric, Draga ; Tedgård, Ulf ; Giles, Jodie E. ; Alvaro, Frank ; Jonsson, Olafur G. ; Mechinaud, Françoise ; Saks, Kadri ; Catchpoole, Daniel ; Kotecha, Rishi S. ; Dalla-Pozza, Luciano ; Chenevix-Trench, Georgia ; Trahair, Toby N. ; Macgregor, Stuart ; Schmiegelow, Kjeld
in: Cancers, vol: 12, issue: 5

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.3390/cancers12051285

  PDF

Metabolic engineering of Aspergillus niger via ribonucleoprotein-based CRISPR–Cas9 system for succinic acid production from renewable biomass

Yang, Lei ; Henriksen, Mikkel Møller ; Hansen, Rasmus Syrach ; Lübeck, Mette ; Vang, Jesper ; Andersen, Julie Egelund ; Bille, Signe ; Lübeck, Peter Stephensen
in: Biotechnology for Biofuels, vol: 13, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1186/s13068-020-01850-5

  PDF

Nationwide germline whole genome sequencing of 198 consecutive pediatric cancer patients reveals a high frequency of cancer prone syndromes

Byrjalsen, Anna ; Hansen, Thomas V.O. ; Stoltze, Ulrik K. ; Mehrjouy, Mana M. ; Barnkob, Nanna Moeller ; Hjalgrim, Lisa L. ; Mathiasen, René ; Lautrup, Charlotte K. ; Gregersen, Pernille A. ; Hasle, Henrik ; Wehner, Peder S. ; Tuckuviene, Ruta ; Sackett, Peter Wad ; Laspiur, Adrian O. ; Rossing, Maria ; Marvig, Rasmus L. ; Tommerup, Niels ; Olsen, Tina Elisabeth ; Scheie, David ; Gupta, Ramneek ; Gerdes, Anne-Marie ; Schmiegelow, Kjeld ; Wadt, Karin
in: PLOS Genetics, vol: 16, issue: 12

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1371/journal.pgen.1009231

 

Nationwide Germline Whole Genome Sequencing of 198 Consecutive Pediatric Cancer Patients Reveals a High Incidence of Cancer Prone Syndromes

Byrjalsen, A. ; Hansen, T. ; Stoltze, U. ; Mehrjouy, M. ; Barnkob, N. ; Hjalgrim, L. ; Mathiasen, R. ; Lautrup, C. ; Gregersen, P. ; Hasle, H. ; Wehner, P. ; Tuckuviene, R. ; Sackett, P. ; Laspiur, A. ; Rossing, M. ; Marvig, R. ; Tommerup, N. ; Olsen, T. ; Scheie, D. ; Gupta, R. ; Gerdes, A-M ; Schmiegelow, K. ; Wadt, K.
in: Pediatric Blood and Cancer, vol: 67, issue: Suppl. 4, pages: S323-S323

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    Year: 2020

  PDF

Polygenic risk score-analysis of thromboembolism in patients with acute lymphoblastic leukemia

Jarvis, Kirsten Brunsvig ; Nielsen, Rikke Linnemann ; Gupta, Ramneek ; Hede, Freja Dahl ; Huttunen, Pasi ; Jónsson, Ólafur Gisli ; Rank, Cecilie Utke ; Ranta, Susanna ; Saks, Kadri ; Trakymiene, Sonata Saulyte ; Tuckuviene, Ruta ; Tulstrup, Morten ; Ruud, Ellen ; Schmiegelow, Kjeld ; LeBlanc, Marissa
in: Thrombosis Research, vol: 196, pages: 15-20

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1016/j.thromres.2020.08.015