Ditte Bentsen

PhD project by Ditte Bentsen Christensen

Name: Ditte Bentsen Christensen
Project Title: Deranged Neurometabolism in Alzheimer's Disease with Hyperpolarized Magnetic Resonance
Group: HYPERMAG
Supervisors: Jan Henrik Ardenkjær-Larsen and Mathilde Hauge Lerche

Project Description: 
Using hyperpolarized magnetic resonance spectroscopy and imaging, this project aims to investigate the changes in the energy metabolism in the brain of Alzheimer’s disease mouse models. The project is in collaboration with the University of Queensland, Australia, where the in vivo mouse study will take place.

Perspective:
The link between Alzheimer’s disease and changes in the neurometabolism is not well understood. However, it might be the key to finding out what causes this devastating disease. Hyperpolarized magnetic resonance is safe for use in humans and thus this project may offer avenues not only for understanding the underlying disease mechanism but also for improved staging of Alzheimer’s disease patients in the clinic.

 

Contact

Contact

Jan Henrik Ardenkjær-Larsen
Interim Head of Department, Professor
DTU Health Tech
+45 45 25 39 18

Contact

Mathilde Hauge Lerche
Senior Researcher
DTU Health Tech
+45 45 25 36 76