Martin Wiinberg

PhD project by Martin Wiinberg

Name: Martin Wiinberg
Project Title: Therapeutic validation of novel drug delivery strategies and their combination with adoptive cell transfer in murine cancer models
Group: Colloids & Biological Interfaces (CBIO)
Supervisors: Thomas Lars Andresen, Ditte Elisabeth Jæhger and Merete Hædersdal (Bispebjerg Hospital)

Project Description: 
Great clinical results have been accomplished in strengthening the immune system’s ability to fight cancer. However, a substantial number of patients experience toxicities related to systemic administration of immunotherapies. The overall objective of this project is to validate novel delivery strategies of immunomodulatory drugs to broaden the applicability of immunotherapies by limiting toxicities related to treatment. As part of the SCIN-CAG collaboration1 with Bispebjerg Hospital, the project will primarily focus on skin cancers which have an unmet need for therapies that prevent the reoccurrence of disease by promoting tumor immunity. The interdisciplinary SCIN-CAG collaboration opens up for clinically relevant models of skin cancer which will be utilized to validate treatments through in-depth analysis using advanced flow cytometry and transcriptional analysis of immune cells. 

Perspective:
Skin cancers are not only the most common type of cancer but also a growing socio-economic burden due to an increasing number of incidences. The close collaboration with Bispebjerg Hospital gives great opportunities to evaluate the therapies in models that resemble human skin cancers, thus improving the likelihood of the therapies making it from bench-to-bedside.  

Skin Cancer Innovation Clinical Academic Group (SCIN CAG)
 

Kontakt

Martin Wiinberg
Ph.d.-studerende
DTU Sundhedsteknologi
27 58 48 56

Kontakt

Thomas Lars Andresen
Professor
DTU Sundhedsteknologi
25 37 44 86

Kontakt

Ditte Elisabeth Jæhger
Postdoc
DTU Sundhedsteknologi